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合并用药治疗耕牛血吸虫和肝片吸虫病研究

STUDY ON THE TREATMENT FOR SCHISTOSOMA JAPONICUM AND FASCIOLA HEPATICA INFECTIONS WITH MIXED TWO DRUGS IN CATTLE
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摘要 本研究通过单项药物的选择试验,合并用药的治疗试验,人工感染日本血吸虫和肝片吸虫病治疗试验,田间扩大治疗等研究。提出硝硫氰醚15mg/kg与三氯苯唑(黄牛3~5mg/kg,水牛8mg/kg)或丙硫咪唑10mg/kg合并第三胃一次投药,对日本血吸虫和肝片吸虫的灭虫率和转阴率达97.5~100%,临床观察,毒性试验,生理生化指标测定说明,临床使用安全,疗效高,比口服节省药物三分之二,节省人力时间一倍,达到一针治疗两病的作用。 オhe study was conducted to compare the curative effects of mixed two drugs treatment (nitroscanata mixed with Fasinex or albendazola)by direct injection into the third stomach with single drug treatment by oral intake,for curing schistosoma Japonicum and fasciola hepatica infections in cattle.Experiments including selection for different single drug,therapeutics of mixed two drugs and cure of artificial infection with the above mentioned parasites in cattle were carried out.The results showed that 97.5~100% schistosoma Japouicum and fasciola hepatica in catte were killed and the animals then turned to negative,when nitrosacnata (15mg/kg B.W)was mixed with fasinex(3~5mg/kg B.W for cattle,8 mg/kg B.W.for buffalo)or albendazole (10mg/kg B.W).Clinical observation,poisonous trial and physiologicbiochemical determination indicated that clinical use of the mixed two trugs treatment was safe an effetive,and saved drug dosage by 66.7%,manpower by 50% and time by 50%,comparing with single drug.It is proved that mixed two drugs is an effective treatment to cure the two diseases simultaneously.
出处 《畜牧兽医学报》 CAS CSCD 北大核心 1997年第6期555-561,共7页 ACTA VETERINARIA ET ZOOTECHNICA SINICA
基金 四川省畜牧局血防经费资助
关键词 合并用药 日本血吸虫病 肝片吸虫病 牛病 耕牛 Schistosoma Japonicum,Fasciola hepatica,Mixed two drugs,Cattle
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参考文献5

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