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辅酶Q_9的合成

Synthesis of Coenzyme Q_9
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摘要 以辅酶Q0为起始原料,经Diels-Alder加成,缩合和逆Diels-Alder分解反应,合成了辅酶Q10的类似物辅酶Q9,总收率61.9%。中间体和Q9的结构经1H NMR和EI-MS表征。 Coenzyme Q9, the analog of coenzyme Q10, was synthesized from coenzyme Q0 by Diels - Aider cycloaddition, condensation and retro-Diels -Aider decomposition. The overall yield was 61.9%. The structures of intermediate and coenzyme Q9 were confirmed by ^1H NMR and EI-MS.
作者 金文虎 许煦 段梅莉 冀亚飞
机构地区 华东理工大学药学院 华东理工大学化工学院
出处 《合成化学》 CAS CSCD 2008年第4期481-482,486,共3页 Chinese Journal of Synthetic Chemistry
关键词 辅酶Q9 Diels—Alder反应 环戊二烯 辅酶Q9 coenzyme Q0 Diels- Alder reaction cyclopentadiene coenzyme Q9
分类号 O623.122 [理学—有机化学] R914.5 [医药卫生—药物化学]
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参考文献9

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共引文献1

合成化学
2008年 第4期

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