儿童中枢性尿崩症的MRI诊断价值

Diagnostic value of MRI in central diabetes insipidus in children

目的:探讨磁共振成像(MRI)在儿童中枢性尿崩症(CDI)中的应用价值。材料和方法:对18例临床确诊为儿童CDI患者的MRI平扫及增强检查结果进行回顾性分析。结果:18例CDI患儿垂体后叶T1WI高信号均消失。其中颅咽管瘤7例,生殖细胞瘤2例,下丘脑-垂体区占位性病变3例,3例垂体柄和/或下丘脑漏斗部局限性梭形或球形增粗,单纯垂体后叶T1WI高信号消失者3例。结论:基于儿童CDI自身的特点,MRI平扫及增强扫描对诊断儿童CDI及寻找其病因具有重要价值。垂体后叶T1WI高信号消失是儿童CDI的非特异性MRI指标。

Objective： To evaluate the diagnostic value of MRI in central diabetes insipidus （CDI） in children. Materials and Methods- MRI findings of 18 children with CD1 were analyzed retrospectively. All 18 patients underwent the conventional and contrast enhanced MRI scanning of the pituitary gland, and were confirmed to be CDI by cliniegl diagnosis. Results： The absence of posterior pituitary hyperintensity showed by MRI in all 18 children with CDI. The lesions located in the hypothalamus-pituitary region in 15 patients. The posterior lobe of pituitary gland was not enhanced in 3 patients which merely have the absence of posterior pituitary hyperintensity. Conclusions： The conventional and contrast enhanced MRI scanning is valuable in the diagnosis and search for the etiology of CDI in children according to its features. The absence of posterior pituitary hyperintensity serves as a nonspecific indicator of CDI.