摘要
A novel synthetic strategy for the construction of 4＇-spironucleosides via cascade radical translocation cyclization of N-allyl-N-（2＇-bromophenyl） amide moiety of 5＇-carboxylic nucleosides and the N-propynyl analogues is described. The conformationally restricted nucleosides herein synthesized are of potentially biological interests.
A novel synthetic strategy for the construction of 4＇-spironucleosides via cascade radical translocation cyclization of N-allyl-N-（2＇-bromophenyl） amide moiety of 5＇-carboxylic nucleosides and the N-propynyl analogues is described. The conformationally restricted nucleosides herein synthesized are of potentially biological interests.
基金
the National Natural Science Foundation of China(No.20572034)
