期刊文献+

凋亡抑制蛋白survivin与恶性肿瘤 被引量:2

下载PDF
导出
摘要 survivin作为IAP家族的新成员,因其独特的肿瘤特异性日益受到重视,它参与了肿瘤发生发展的诸多环节,与肿瘤的发生发展密切相关;在肿瘤的诊断、治疗、预后中均有价值。本文就survivin的生物学特性、功能作用机制、在肿瘤中的表达、临床意义以及作为肿瘤基因靶点治疗等方面进行综述。
出处 《中国医药导报》 CAS 2008年第22期20-21,共2页 China Medical Herald
  • 相关文献

参考文献18

  • 1[1]Guo M,Hay BA.Cell proliferation and apoptosis[J].Curt Opin Cell Biol 1999,11(6):745-752.
  • 2[2]Given M,Scott M,Mc Grath JP,et al.The predictive of tumour markers CA 15-3,TPS and CEA in breast cancer recurrence[J].Pathol,2000,9(5):277-280.
  • 3[3]Kobayashi K,Hatano M,Ogasawara T,et al.Expreasion of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation[J].Proc Natl Acad Sci USA,1999,96(4):1457-1462.
  • 4[4]Adida C,Crotly PL,McGrath J,et al.Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation[J].Am J Pathol,1998,152 (1):43-49.
  • 5[5]O'Conner DS,Schechner JS,Adida C,et al.Control of apoptosis during angiogenesis by survivin expression in endothelial cells[J].Am J Pathol,2000,156(2):393-398.
  • 6[6]Mesri M,Morahs-Rniz M,Ackermann EJ,et al,Suppression of vascular endothelial growth factor-mediated endothelial cells protection by survivin targeting[J].Am J Pathol,2001,158(5):1757-1765.
  • 7[7]Ito T,Shiraki K,Sugimoto K,et al.Survivin promotes cell proliferation in human bepatocellular carcinoma[J].Hepatology,2000,31(5):1080-1085.
  • 8[8]Lu CD,Altieri DC,Tanignwa N.Expression of a novel antiapoptesis gene,survivin,correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas[J].Cancer Res,1998,58(9):1808-1812.
  • 9[9]Kawasaki H,Ahieri DC,Lu CD,et al.Inhibition of apoptosis by survivin predicts shorter survival rates in coloroctal cancer[J].Concer Res,1998,58(22):5071-5074.
  • 10[10]Tanaka K,Iwamoto S,Gon G,et al.Expression of survivin and its relationship to loss of apoptosis in breast carcinomas[J].Clin Cancer Bee,2000,6(1):127-134.

同被引文献14

  • 1高再荣,张凯军,张永学.MAG_3和DTPA用于^(99)Tc^m标记Survivin ASON的对比研究[J].中华核医学杂志,2004,24(4):238-241. 被引量:5
  • 2常晓华,姜爱民,张超,梁桃,宋吉涛,郭晓华.大肠癌中Survivin、PTEN、p16的表达及其临床意义[J].中国临床医学,2007,14(1):31-32. 被引量:5
  • 3Fuzhong T,Nan L,Jiajia G,et al. Clinical significance of the relationship between expression of survivin and effects of neoadjuvant chemotherapy in locally advanced breast cancer [ J ]. Gan To Kagaku Ryoho,2008,35 ( 8 ) : 1319 - 1323.
  • 4Mita AC, Mita MM, Nawrocki ST, et al. Survivin : key regulator of mitosis and apoptosis and novel target for cancer therapeutics[ J]. Clin Cancer Res,2008,14(16) :5000 -5005.
  • 5Kato J, Kuwabara Y, Mitani M, et al. Expression of survivin in esophageal cancer: correlation with the prognosis and response to chemotherapy [ J ]. Int J Cancer,2001,95 (2) :92 - 95.
  • 6Adida C, Recher C, Raffoux E, et al. Expression and prognostic significance of survivin in de novo acute myeloid leukaemia[ J]. Br J Haematol,2000,111 ( 1 ) : 196 - 203.
  • 7Haghpanah V, Shooshtarizadeh P, Heshmat R, et al. Immunohistochemical analysis of survivin expression in thyroid follicular adenoma and carcinoma [ J ]. Appl Immunohistochem Mol Morphol, 2006,14(4) :422 -425.
  • 8Lu YH, Luo XG, Tao X. Survivin gene RNA interference induces apoptosis in human HL60 leukemia cell lines [ J ]. Cancer Biother Radiopharm,2007,22 ( 6 ) : 819 - 825.
  • 9陈健,杨清绪,朱淑玲.Survivin在原发性肝癌组织中的表达[J].中国现代医生,2008,46(2):21-22. 被引量:1
  • 10周木秀,涂抗美,栗娜,黄虎.中青年乳腺癌组织中survivin表达的临床意义[J].中国现代医生,2008,46(25):98-99. 被引量:1

引证文献2

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部