摘要
世界上感染乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)的人数超过五亿,他们随时都可能演变成慢性肝病、肝硬化甚至肝癌。尽管乙型肝炎病毒与丙型肝炎病毒的致病机制有许多相似之处,但是它们的病毒生理特征以及免疫逃避和存活机制却有很多的不同。本文叙述了这两种病毒性肝病的研究进展,阐述了乙型肝炎病毒和丙型肝炎病毒的感染机制,并对以后的研究进行了展望。
More than 500 million people worldwide are persistently infected with the hepatitis B virus(HBV) and/or hepatitis C virus(HCV) and are at risk of developing chronic liver disease, cirrhosis and hepatoeellular carcinoma. Despite many common features in the pathogenesis of HBV-and HCV-related liver disease,these viruses markedly differ in their virological properties and in their immune escape and survival strategies. This review assesses recent advances in our understanding of viral hepatitis, contrasts mechanisms of virus-host interaction in acute hepatitis B and hepatitis C, and outlines areas for future studies.
出处
《中国现代医生》
2008年第21期255-256,共2页
China Modern Doctor