慢性肺源性心脏病继发肺部真菌感染63例临床分析

The Clinical Analysis about 63 Cases of Chronic Pulmonary Heart Disease Followed by Pulmonary Mycosis

目的探讨肺源性心脏病患者肺部真菌感染的发病因素及其临床诊治。方法对63例肺心病患者肺部真菌感染的临床资料进行回顾性分析。结果观察组年龄>70岁43例(占68.26%)、平均住院时间23.5d、应用抗生素种类多、时间长(平均13.5d)、使用糖皮质激素时间长(>10d),与对照组比较差异均具有显著性(P<0.01)。结论预防肺心病继发肺部真菌感染的主要措施是积极治疗原发病,合理应用抗生素,慎用激素,同时注意营养、支持治疗,缩短肺心病的住院天数,早期诊治真菌感染。

Objective To discuss the causes, diagnosis and treatment of pulmonary mycosis happening in the patients of chronic pulmonary heart disease （chronic cor pulmonale）. Methods To analyze retrospectively the clinical data of 63 patients of chronic pulmonary heart disease followed by pulmonary mycosis. Results There was significant difference （P〈0.01） between the observation group and the control group in the following aspects： in the observation group,43 patients of age 〉70 years（68.26%）,average stay of 23.5 days,the treatment including more kinds of antibiotics and longer course（average 13.5 days ） ,long-time use of glucocorticoid（ 〉10 days）. Conclusion The measures to prevent the chronic pulmonary heart disease followed by pulmonary mycosis include these aspects： the effective treatment of primary disease,the reasonable use of antibiotics,the careful use of glucocorticoid, the nutrition support,shortening the average stay and the early diagnosis of mysotic infection.