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硅油对角膜内皮细胞的影响 被引量:4

The Effect of Silicone Oil Injection Corneal Endothelium
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摘要 目的探讨硅油填充术后角膜内皮细胞的改变。方法选择在我院行硅油填充术的患者81例(81眼),按手术方式分为2组:第1组为行玻璃体切割联合硅油填充术的患者,即保留晶体组;第2组为行玻璃体切割联合晶体切除及硅油填充术的患者,即无晶体组,分别于术前、术后1周、1个月、3个月、6个月对角膜内皮中央区进行活体摄像,计算角膜内皮细胞密度并进行图像处理和结果分析。结果所有患者的角膜内皮细胞密度均较术前有明显下降,差异有显著性。第1组患者角膜内皮细胞密度在术后1周左右就基本保持稳定,第2组患者角膜内皮细胞密度在术后仍有一定的下降趋势,在术后1个月左右基本稳定。两组患者的角膜内皮细胞密度比较,在术前时差异无显著性(P>0.05);在术后1周、术后1个月、术后3个月、术后6个月随访时差异均有显著性(P<0.05)。结论玻璃体切割硅油填充手术对角膜内皮有损害。术中保留晶体对保护角膜内皮有重要意义。当确定视网膜复位后,应尽早取出硅油。 Objective To study the changes of corneal endothelium after silicone oil tamponade. Methods This trial involved 81 cases (81 eyes) who received vitrectomy with tamponade of silicone oil or vitrectomy and lensectomy with tamponade of silicone oil. The changes of corneal endothelium were observed before surgery and l week, 1 month, 3 month, 6 month after surgery. Results The mean corneal endothelial cell densities was significantly decreased after surgery in all cases (P〈0.05 ). The mean corneal endothelial cell densities was decreased significantly in phakic eyes than in aphakic eye with tamponadc of silicone oil during follow - up( P〈0.05 ). Conclusion Vitrectomy with silicone oil tamponade could damage the corneal endothelium. Retention of lens may protect corneal endothelium from injury in silicone tamponaded cases. The silicone oil should be extracted as early as possible.
出处 《医学研究杂志》 2008年第8期110-111,共2页 Journal of Medical Research
关键词 角膜内皮细胞密度 玻璃体切割 硅油 Corneal endothelial cell density Vitrectomy Silicone oil
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参考文献3

  • 1Friberg TR, Doran DL, Lazenby FL. The effect of vitreous and retinal surgery on corneal endothelial cell density. Ophthalmology, 1984,91 (10) :1166 - 1169
  • 2黎晓新,王景昭.玻璃体视网膜手术学.北京:人民卫生出版社,1998:154-155
  • 3Matsuda M ,Tano Y,Inaba M ,et al. Corneal endothelial cell damage associated with intraocular gas tamponade during pars plana vitrectomy. Jpn J Ophthalmol, 1986,30(3) :324 -329

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