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肌细胞增强因子2A基因与冠心病相关性的研究进展 被引量:1

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摘要 冠心病的遗传因素尚不明确,肌细胞增强因子2A基因突变可能与冠心病有关。但此基因与冠心病之间相关机制仍不清楚,本文就肌细胞增强因子2A基因与冠心病相关性的最新研究进展作一综述。
作者 赵旺 彭道泉
出处 《中国动脉硬化杂志》 CAS CSCD 2008年第4期326-328,共3页 Chinese Journal of Arteriosclerosis
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参考文献28

  • 1Greenland P, Knoll MD, Stamler J, et al. Major risk factors as antecedents of fatal and nonfatal coronary heart disease events [ J]. JAMA, 2003, 290(7) : 891-897.
  • 2Lusis AJ, Mar R, Pajukanta P.Genetics of atherosclerosis[J].Annu Rev Genomisc Hum Genet, 2004, 5: 189-218.
  • 3Smith rD, Tepol EJ.1dentification of atherosclerosis-modifying genes:pathogenic insights and therapeutic potential[J].Expert Rev Cardiovasc Ther,2006, 4 (5): 703-709.
  • 4Hobson GM,Krahe R,Garcia E,et al.Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2(MEF2)gene family to human chromosomes 15q26,19p12,5q14,and1q12-q23[J].Genomics, 1995, 29 (3): 704-711. .
  • 5张文炜,徐列明.转录因子MEF2对多种信号通路的调节及其生物学作用[J].中国生物化学与分子生物学报,2004,20(4):423-427. 被引量:20
  • 6Karamboulas C.Dakubo GD,Liu J,et al.Disruption of MEF2 activity in cardiomyoblasts inhibits cardiomyogenesis [J]. J Cell Sci, 2006, 119 (Pt 20): 4315-321. .
  • 7Wang YX, Qian LX, Liu D, et al. Bone morphogenetic protein-2 acts upstream of myocyte-specific enhancer factor 2a to control embryonic cardiac contractility[J].Cardiovasc Res ,2007, 74 (2): 290-303. .
  • 8Wang L, Fan C, Topoi SE, et al. Mutation of MEF2A in an inherited disorder withfeatures of coronary artery disease [J]. Science, 2003, 302 (5650): 1578-581.
  • 9Bhagavatula MR, Fan C, Shen GQ, et al. Transcription factor MEF2A mutations in patients with coronary artery disease [ J ]. Hum Mol Genet, 2004, 13(24) : 3 181-188.
  • 10Weng L, Kavaslar N,Ustaszewska A,et la.Lack of NEF2A mutations in coronary artery disease [J].J Clin Invest, 2005, 115 (4) : 1016-020.

二级参考文献93

  • 1Yong Yong SHI,Lin HE.SHEsis,a powerful software platform for analyses of linkage disequilibrium,haplotype construction,and genetic association at polymorphism loci[J].Cell Research,2005,15(2):97-98. 被引量:381
  • 2Nigel J B. Molecules in focus myocyte enhancer factor 2 (MEF2). Int J Biochem Cell Biol,1997, 29 (12) :1467 - 1470
  • 3Black B L, Olson E N. Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annu Rev Cell Dev Biol,1998, 14: 167- 196
  • 4Lilly B, Galewsky S, Firulli A B, Schulz R A, Olson E N. D-MEF2:a MADS box transcription factor expressed in differentiating mesoderm and muscle cell lineages during Drosophila embryogenesis. Proc Natl Acad Sci USA, 1994, 91(12):5662~5666
  • 5Nguyen H T, Bodmer R, Abmayr S M, Mcdermott J C, Spoerel N A.D-mef2: a Drosophila mesoderm-specific MADS boxcontaining gene with a biphasic expression profile during embryogenesis. Proc Natl Acad Sci USA, 1994, 91(16) :7520 ~ 7524
  • 6Han J, Jiang Y, Li Z, Kravchenko W, Ulevitch R J. Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation.Nature, 1997, 38(6) :296 - 299
  • 7Lu J, Mckinsey T A, Zhang C L, Olson E N. Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class Ⅱhistone deacetylases. Mol Cell, 2000, 6(2 ): 233 - 244
  • 8Zetser A, Gredinger E, Bengal E. p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the MEF2C transcription factor. J Biol Chem, 1999, 274(8) :5193 - 5200
  • 9Puri PL, WuZ, Zhang P, Wood L D, Bhakta K S, Han J, Feramisco J R, Karin M, Wang J Y. Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosatcoma cells. Genes Dev ,2000,14(5) :574 ~ 584
  • 10Mao Zixu, Bonni A, Xia Fen, Mireya N V, Michael E G. Neuronal activity-dependent cell survival mediated by transcription factor MEF2.Science, 1999, 286(5440) :785 - 790

共引文献123

同被引文献19

  • 1戴大鹏,何青,周晓阳,肖尧,张志欣,钱贻简,蔡剑平.MEF2A基因CAG三联核苷酸重复序列与冠状动脉粥样硬化性心脏病的相关研究[J].中华老年心脑血管病杂志,2006,8(10):671-674. 被引量:8
  • 2杨勇,韩雅玲.MEF2转录因子家族与心脏发育及心血管系统相关疾病的关系[J].国际病理科学与临床杂志,2007,27(2):161-164. 被引量:1
  • 3Liu G, Hall J, Profirovic J, et al. Galpha13 regulates MEF2-dependent gene transcription in endothelial eeUs: role in angiogenesis [ J ]. Angiogenesis, 2009, 12 ( 1 ) : 1-15.
  • 4Liopeta K, Boubali S, Virgilio L, et al. cAMP regulates IL-10 production by normal human T lymphocytes at multiple levels : a potential role for MEF2 [J]. Mol Immunol, 2009, 46 (3) : 345-354.
  • 5Pollock R, Treisman R. Human SRF-related proteins: DNA-binding properties and potential regulatory targets [ J]. Genes Dev, 1991,5 (12A) : 2 327-341.
  • 6Yu YT, Breitbart RE, Smoot LB, et al. Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors [J]. Genes Des, 1992, 6 (9) : 1 783-798.
  • 7Edmondson DG, Lyons GE, Martin JF, et al. MEF2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis [J]. Development, 1994, 120 (5) : 1 251-263.
  • 8Ikeda S, He A, Kong SW, et al. MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and MEF2a genes [ J]. Mol Cell Biol, 2009, 29 (8) : 2 193-204.
  • 9Xu J, Gong NL, Bodi I, et al. Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenie mice[J]. J Biol Chem, 2006, 281 (14): 9 152-162.
  • 10Naya FJ, Black BL, Wu H, et al. Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor [ J ]. Nat Med, 2002, 8 ( 11 ) : 1 303-309.

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