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奥沙利铂联合表阿霉素及5氟尿嘧啶治疗晚期胃癌 被引量:2

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摘要 目的观察奥沙利铂联合表阿霉素及5氟尿嘧啶(5-FU)治疗晚期胃癌的近期疗效及安全性。方法表阿霉素50mg/m^2,静脉注射,dl;奥沙利铂100mg/m^2静脉滴注2h,dl;5-FU 500mg/m^2持续静脉泵入120h,每3周重复,每位患者至少接受3个周期化疗评价疗效。结果共31例入组,均可评价疗效及不良反应。患者总有效率(RR:CR+PR)41.9%,SD38.7%,PD19.4%。Ⅲ~Ⅳ度不良反应主要为:中性粒细胞减少19.4%,贫血3.2%,血小板减少9.7%,恶心呕吐3.2%。结论本研究显示,此方案治疗晚期胃癌疗效肯定,不良反应能够耐受。
出处 《安徽医学》 2008年第5期590-591,共2页 Anhui Medical Journal
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