摘要
目的:观察大剂量环磷酰胺(HD-CTX)治疗重型再生障碍性贫血(SAA)的疗效。方法:对照组使用环孢素A(CSA)以及大剂量丙种球蛋白、甲基强的松龙、雄激素等治疗;治疗组在对照组的基础上加用环磷酰胺45mg/kg.d,连用4d。结果:治疗组10例总有效率为80%;对照组12例总有效率50%。结论:大剂量环磷酰胺治疗SAA是一种有效、可行的治疗方法。
Objective： To observe the effective method of treating childhood acute aplastic anemia with high-dose cyclophosphamide. Methods： The control group were treated by ciclosporin A, high dose of methyllprednisolone, large dose of gamma globulin and androgen, in the therapy group , high-dose cyclo-phosphamide were added to treating SAA. Results：The total effective rates of treating SAA children in the therapy group and control group were 80 % and 50 % , respectively. Conclusion： High-dose cyclophos-phamide in treating childhood acute aplastic anemia is a safe and feasible method.
出处
《河北医学》
CAS
2008年第9期1028-1029,共2页
Hebei Medicine
