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强化胰岛素治疗严重创伤应激性高血糖疗效观察 被引量:4

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摘要 目的 研究强化胰岛素治疗对严重创伤患者术后血糖控制水平与预后的关系。方法选择至少在ICU监护5d,APACHEⅡ评分18分以上,既往无糖尿病病史的严重创伤术后患者48例。收住ICU时血糖水平(16±4)mmol/L,随机分为2组,均给予静脉泵入胰岛素控制血糖。A组(n=24)控制血糖在4.4~6.1mmol/L;B组(n=24)控制血糖8.3~11.1mmol/L;观察2组患者需机械通气天数、脓毒血症发生率、应激性溃疡发生率、院内感染发生率、多脏器功能衰竭(MOF)发生率、低血糖发生率、病死率等参数。结果 A组在需机械通气天数、脓毒血症发生率、应激性溃疡发生率、院内感染发生率、多脏器功能衰竭(MOF)发生率、病死率均明显低于B纽,但低血糖发生率A纽明显高于B组(P〈0.05)。结论 对于严重创伤术后患者强化胰岛素治疗将血糖水平控制在4.4~6.1mmol/L可改善严重创伤患者的病情,降低病死率。
出处 《河北医药》 CAS 2008年第8期1134-1135,共2页 Hebei Medical Journal
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参考文献9

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