我院2005～2007年102例药品不良反应报告分析

Analysis of 102 ADR Cases Occurred from 2005 to 2007 in Our Hospital

目的:了解我院药品不良反应(ADR)发生的特点。方法:对我院2005～2007年102例ADR报告,从患者性别、年龄、给药途径、药品种类以及临床表现等方面进行统计、分析。结果:102例ADR中,女性占总例数的65.69%(67例);以静脉滴注方式给药引起的ADR占总例数的90.20%(92例);最易引起ADR的药品为抗感染药,占总例数的84.31%(86例);最常见的临床表现为皮肤及其附件损害,占总例数的74.51%(76例)。结论:应加强ADR监测报告工作,减少或避免ADR的发生。

OBJECTIVE： To investigate the characteristics of adverse drug reactions （ADR） occurrred in our hospital. METHODS： 102 ADR cases collected from 2005 to 2007 in our hospital were analyzed in respect of the patients＇ age and sex, route of administration, drug species and clinical manifestation etc. RESULTS ： In 102 ADR cases, 67 （65.69%） were female, 92 （90.20%） were induced by intravenous drop infusion, 86 （84.31%） were related to anti- infectives, and 76 eases （74.51%） manifested as lesion of skin and its appendants. CONCLUSION： ADR monitor work should be strengthened to avoid or reduce the incidence of ADR.