期刊文献+

材料科学中的点击化学 被引量:19

"Click" Chemistry in Materials Science
下载PDF
导出
摘要 近年来,点击(click)化学反应以其高产率、高选择性以及对各种官能团和反应条件优异的耐受性成为材料科学家们手中有力的研究工具。本文综述了点击化学的概念、特点、反应机理及应用。重点介绍了点击化学反应在聚合物、表面修饰、纳米材料方面的研究进展,并分析了点击化学目前存在的不足及今后发展趋势。 In recent years, click reactions have converged into a powerful tool set for materials scientists because of their high yields, high selectivity, and exceptional tolerance towards a wide range of functional groups and reaction conditions. In this paper, the conception, characteristic, reactive mechanism and applications of click chemistry are reviewed. In particular, applications of click chemistry in the modification of polymers, surfaces and nanomaterials are reviewed. The problem of click chemistry and the trend in the future are analyzed.
出处 《化学进展》 SCIE CAS CSCD 北大核心 2008年第7期1090-1101,共12页 Progress in Chemistry
关键词 点击化学 聚合物 树枝状聚合物 表面修饰 纳米材料 "click" chemistry polymers dendrimers surface modification nanomaterials
  • 相关文献

参考文献95

  • 1仇文卫,李静雅,李佳,南发俊.“Click”化学在药物发现中的应用[J].生命科学,2006,18(3):295-302. 被引量:2
  • 2LutzJ F. Angew. Chem. Int. Ed., 2007, 46:1018-1025.
  • 3Gierlich J, Burley G A, Carell T, et al. Organic Letters, 2006, 8 : 3639-3642.
  • 4Such G K, Quinn J F, Caruso F, et al. J. Am. Chem. Soc., 2006, 128:9318-9319.
  • 5Lee J K, Chi Y S, Choi I S. Langmuir, 2004, 20:3844-3847.
  • 6Dorsselaer A V, Albrecht-Gary A M, Nierengarten J F, et al. Angew. Chem. Int. Ed., 2005, 44:5338-5341.
  • 7Helms B, Mynar J L, Frechet M J, et al. J. Am. Chem. Soc., 2004, 126:15020-15021.
  • 8Englert B C, Bakbak S, Bunz U H F. Macromolecules, 2005, 38:5868-5877.
  • 9Khanttskyy B, Dallinger D, Kappe C O. J. Comb. Chem., 2004, 6:884-892.
  • 10Speers A E, Adam G C, Cravatt B F. J. Am. Chem. Soc., 2003, 125 : 4686-4687.

二级参考文献26

  • 1Naylor S.Proteomics:the "omic" technology hole in drug discovery and development.Drug Discov Today:Targets,2004,3:S1~S2
  • 2Kolb H C,Finn M G,Sharpless K B.Click chemistry:diverse chemical function from a few good reactions.Angew Chem Int Ed Engl,2001,40(11):2004~2021
  • 3Kolb H C,Sharpless K B.The growing impact of click chemistry on drug discovery.Drug Discov Today,2003,8(24):1128~1137
  • 4Saxon E,Bertozzi C R.Cell surface engineering by a modified staudinger reaction.Science,2000,287(5460):2007~2010
  • 5Kiick K L,Saxon E,Tirrell D A,Bertozzi C R.Incorporation of azides into recombinent proteins for chemoselective modification by staudinger ligation.Proc Natl Acad Sci USA,2002,99(1):19~24
  • 6Huisgen R.1,3-Dipolar Cycloaddition.Angew Chem Int Ed Engl,1963,2:565~598
  • 7Prescher J A,Bertozzi C R.Chemistry in living systems.Nat Chem Biol,2005,1(1):13~21
  • 8Link A J,Tirrell D A.Cell surface labeling of Escherichia coli via copper(Ⅰ)-catalized[3+2] cycloaddition.J Am Chem Soc,2003,125(37):11164~11165
  • 9Agard N J,Prescher J A,Bertozzi C R.A strain-promoted[3+2]azide alkyne cycloaddition for covalent modification of biomolecules in living systems.J Am Chem Soc,2004,126(46):15046~15047
  • 10Lee L V,Mitchell M L,Huang S J,et al.A potent and highly selective inhibitor of human a-1,3-fucosyltransferase via click chemistry.J Am Chem Soc,2003,125(32):9588~9589

共引文献1

同被引文献429

引证文献19

二级引证文献88

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部