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DNA改组技术及其在蛋白类药物定向进化中的应用 被引量:1

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摘要 自DNA重组(DNA shuffling)技术诞生以来,作为现代生物技术核心的基因工程技术得到了飞速的发展,特别是改组技术在基因重组,分子、蛋白蛋进化等领域得到了快速的发展,开创了定向分子进化的新纪元。和常规进化相比,定向进化具有快速、高效的特点。比随机诱变显著地提高了良性突变的概率,且改组技术的方法巧妙,重点突出,着重实效,
出处 《中国药物与临床》 CAS 2008年第8期589-593,共5页 Chinese Remedies & Clinics
基金 国家自然科学基金面上项目(30771500)
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