沙美特罗、丙酸氟替卡松吸入治疗儿童哮喘的疗效观察

Therapeutic effect of seretide inhalation on children with asthma

目的:观察吸入沙美特罗、丙酸氟替卡松对儿童哮喘的治疗效果。方法:将60例患儿分为治疗组与对照组,治疗组给予沙美特罗、丙酸氟替卡松(舒利选)吸入治疗,对照组给予普米克都保,分别于治疗前及治疗后1、3、6个月测量呼气峰流速(PEF)值,并观察哮喘发作次数、MEF等。结果:与治疗前比较,治疗后1、3、6个月PEF值明显增高,差异有统计学意义(P均<0.05)。哮喘发作次数及MEF治疗前与治疗后差异有统计学意义(P均<0.05)。治疗组临床控制、显效、好转明显优于对照组,两组总有效率比较差异有统计学意义(χ2=29.846,P<0.05)。结论:沙美特罗、丙酸氟替卡松吸入对哮喘患儿具有良好的治疗作用。

Objective：To observe the efficacy of Seretide in the treatment of children with asthma. Methods： Data of 60 asthmatic cases from Jan 2004 to Dec 2006 were gathered and randomly divided into two groups. One group was treated with seretide and the other with budesonide. The percentage of peak flow was measured before and 1,3 and 6 months after treatment. The times of acute onset of asthma and MEF were analyzed statistically. Results： The percentage of peak flow measured 1, 3 and 6 months after treatment were significantly higher than that measured before treatment. The times of acute onset of asthma and MEF were noted with statistical difference. The therapeutic effect of experiment group was better than the control group. Conclusions： Seretide inhalation can bring a satisfactory therapeutic result to children with asthma.