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白细胞介素18(IL-18)的研究进展 被引量:1

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摘要 白细胞介素18(Interleukin-18,IL-18)最初名为干扰素诱生因子(Interferon gamma inducing factor,IGIF)或白细胞介素1r,现已了解它有重要的免疫调节和保护功能。它可诱生IFN—r及Fasl表达,增强IL-2和GM-CSF的活性,可与许多细胞因子相互作用,参与了自身免疫性疾病,变态反应性疾病的发生,在许多疾病的基础性研究和临床应用中有重要前景。现就IL-18的研究现状作一综述。
作者 刘亚普
出处 《中国医药指南(学术版)》 2008年第13期67-70,共4页 Guide of China Medicine
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