加强对胶质细胞瘤综合治疗的临床探索性研究
被引量:1
摘要
胶质细胞瘤(glioma),也称神经胶质细胞瘤,发生于神经外胚叶组织,是中枢神经系统最为常见的原发性肿瘤。过去认为,胶质细胞瘤多见于成年人;目前发现,本病在其他年龄段均有发病率逐渐增高的趋势。颅内压增高,神经系统定位症状和体征,甚至昏迷,是胶质细胞瘤患者常见临床表现,严重影响着患者的生活质量并危及生命。在人类对抗和干预胶质细胞瘤的历史中,
出处
《中华神经外科疾病研究杂志》
CAS
2008年第4期289-292,共4页
Chinese Journal of Neurosurgical Disease Research
基金
陕西省自然科学基金(2005C209)
参考文献23
-
1Fisher JL, Schwartzbaum JA, Wrensch M, et al. Epidemiology of brain tumors [J]. Neurol Clin, 2007, 25(4) : 867 -890.
-
2Stiles CD, Rowitch DH. Glioma stem cells: a midterm exam [ J ]. Neuron, 2005, 55(6): 832-846.
-
3Sulman E, Aldape K, Colman H. Brain tumor stem cells [ J]. Curr Probl Cancer, 2008, 32(3) : 124 - 142.
-
4Heese O, Disko A, Zirkel D, et al. Neural stem cell migration toward gliomas in vitro [J]. Neuro-oncol, 2005, 7(4) : 476 -484.
-
5Tunici P, Bulte .JW, Bruzzone MG, et al. Brain engraftment and therapeutic potential of stem/progenitor cells derived from mouse skin [J]. J Gene Med, 2006, 8(4): 506 -513.
-
6Lorico A, Mercapide J, Soloduschko V, et al. Primary neural stem/ progenitor cells expressing endostatin or cytochrome P450 for gene therapy of glioblastoma [ J]. Cancer Gene Ther, 2008, 18. [ Epub ahead of print].
-
7Wang D, Ruan H, Hu L, et al. Development of a hypoxia-inducible cytosine deaminase expression vector for gene-directed prodrug cancer therapy [J]. Cancer Gene Ther, 2005, 12(3) : 276 -283.
-
8Aboody KS, Najbauer J, Danks MK. Stem and progenitor cellmediated tumor selective gene therapy [ J ]. Gene Ther, 2008, 15 (10) : 739 -752.
-
9Benedetti S, Pirola B, Pollo B, et al. Gene therapy of experimental brain tumors using neural progenitor cells [J]. Nat Med, 2000, 6(4) : 447 -450.
-
10Das S, Raizer JJ, Muro K. Immunotherapeutic treatment strategies for primary brain tumors [J]. Curr Treat Options Oncol, 2008,9( 1 ) : 32-40.
二级参考文献14
-
1于丽,李晓原.光动力学作用诱导肿瘤细胞凋亡的机制[J].中国激光医学杂志,2006,15(1):59-61. 被引量:1
-
2Valtonen S, Timonen U, Toivanen P, et al. Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: a randomized double-blind study [J]. Neurosurgery, 1997, 41(1): 44-49.
-
3Kevin C, Tadashi K, Yasuko K, et al. Molecular response of human glioblastoma multiforme cells to ionizing radiation: cell cycle arrest ,modulation of the expression of cyclin-dependent kinase inhibitors, and autophagy [J]. J Neurosurg, 2003, 98(2): 378-384.
-
4Tribius S, Pidel A, Casper D, et al. ATM protein expression correlates with radioresistance in primary glioblastoma cells in culture [J]. Int J Radiation Oncology Biol Phys, 2001, 50(2): 511-523.
-
5司徒镇强 吴军正.细胞培养 [M].西安:世界图书出版公司,2004.239-245.
-
6Mottolese M, Natali PG, Coli A, et al. Comparative analysis of proliferating cell nuclear antigen and epidermal growth factor receptor expression in glial tumors: correlation with histological grading [J]. Anti cancer Res, 1998, 18(3B): 1951-1956.
-
7Kelman Z. PCNA : structure, functions and interactions [J]. Oncogene, 1997, 14(6): 629-640.
-
8Palazzo JP, Kafka NJ, Grasso L, et al. The role of p53, p21WAF1/CIPI, and bcl-2 in radioresistant colorectal carcinoma [J]. Hum Pathol, 1997, 28(10): 1189-1195.
-
9Bjork-Eriksson T, West CM, Cvetskovska E, et al. The lack of correlation between proliferation(Ki 67, PCNA,LI,Tpot), p53 expression and radiosensitivity for head and neck cancers [J]. Br J Cancer, 1999, 80(9): 1400-1404.
-
10魏华江,林红.激光诱导细胞凋亡的研究概况[J].广东药学院学报,2000,16(4):294-296. 被引量:1
共引文献5
-
1肖玉强,唐海涛,张良玉,曹振宇,付振宇,郄福忠,王凯,鲁春鹤,张磊.三氧化二砷诱导C6胶质瘤细胞凋亡实验研究[J].中华神经外科疾病研究杂志,2007,6(4):315-318. 被引量:3
-
2张晓明,孙捷,胡韶山.光动力联合顺铂治疗大鼠脑胶质瘤的生存期观察[J].神经疾病与精神卫生,2010(3):223-225.
-
3孙影,刘巍,杨方.光动力疗法联合贝伐珠单抗治疗裸鼠U87胶质瘤的实验研究[J].中国激光医学杂志,2011,20(3):149-153. 被引量:1
-
4李波,孟超,鞠东辉,高万龙,丛大忞,胡韶山.光动力治疗联合托拉塞米对大鼠脑胶质瘤的影响研究[J].国际生物医学工程杂志,2017,40(5):346-352.
-
5李容,朱新红,林存智,张华.光动力治疗肿瘤分子机制研究进展[J].中国激光医学杂志,2017,26(6):333-336. 被引量:3
同被引文献21
-
1赵明,李安民,傅相平,张志文,查炜光,易林华.手术联合间质内放疗治疗复发性脑胶质细胞瘤[J].中国临床神经外科杂志,2007,12(6):335-337. 被引量:7
-
2Neyns B, D'Haeseleer M, Rogiers A, et al. The role of cytotoxic drugs in the treatment of central nervous system gliomas [J]. Acta Neurol Belg,2010,110(1) : 1- 14.
-
3Letteboer M M, Willems P W, Viergever M A,et al. Brain shift estimation in imageguided neurosurgery using 3- D uhrasound [ J ]. IEEE Trans Biomed Eng, 2005,52 ( 2 ) :268- 276.
-
4Yordanka N, Yordanova, Ylvide, et al. Awake surgery for WHO grade II gliomas within "noneloquent" areas in the left dominant hemisphere: toward a " supratotal" resection [ J ]. Neurosurgery ,2011, 115:232-239.
-
5Jean regis, Constantin tuleasca. Fifteen years of Gamma Knife surgers for trigenminal neuralgia in the Journal of Neurosurger: history of a revolution in functional neurosurgery [J]. Neurosurgery,2011, 115:2-7.
-
6Singh SK,Hawkins C,Clarke ID,et al. identification of human brain tumour initiating ceils [ J ]. Nature, 2004,432 : 396-401.
-
7Benedetti S, piola B, PolIB, et al. Gene therapy of experimental brain tumors using neural progenitor cells[ J]. Nat Med,2000,6:447-450.
-
8Wang D, Ruan H, Hu L,et al. Development of a hypoxia-inducible cytosine deaminase expression vector for gene directed prodrug cancer therapy [ J ]. Cancer Gene Ther, 2005,12(3) :276-283.
-
9IANF, POi,I,ACK. Multidisciplinary manangement of child-hood brain tumors:a review of outcomes, recent advances, and challenge [ J ]. Neu rosurg Pediaiatrics, 2011, 8 ( 2 ) : 135 - 148.
-
10Stommel JM,et al. Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies [ J ]. Science,2007,318 (5848) :287.
-
1高林瑞,于尔辛.干扰素治疗肝癌的临床探索[J].实用肿瘤学杂志,1989,3(4):43-45. 被引量:1
-
2吴哲褒,周良辅,刘小梅(编辑).应开展中国人群胶质母细胞瘤的分子分型研究[J].中华医学杂志,2012,92(11):721-723. 被引量:1
-
3万百顺,花亚伟,张占东.脾切除在进展期近端胃癌根治术中的临床探索[J].国际肿瘤学杂志,2009,36(7):558-558.
-
4A.Atzinge,B.Dietl,安汉祥.原神经外胚叶肿瘤(PNET)诊断和治疗尝试[J].放射学实践,1992,7(4):166-168. 被引量:1
-
5彭莉,冯波儒.首诊于眼科的胶质瘤患者5例分析[J].基层医学论坛(B版),2006,10(2):179-180.
-
6马秀婵.卵巢癌保守性手术治疗20例临床探索[J].中国卫生标准管理,2015,6(12):185-186.
-
7李勤裕,吴卫泽,韩天权,张圣道.胆管癌的分子靶向治疗[J].世界华人消化杂志,2012,20(14):1171-1177. 被引量:8
-
8张群华,倪泉兴,张延龄.应加大胰腺癌诊治研究的力度[J].中华医学杂志,2002,82(6):361-362. 被引量:14
-
9江涛.从容应对胶质瘤复发[J].医药与保健,2008(6):45-45.
-
10范悦,王世明,石青青.苦参碱对肝癌细胞增殖及其细胞自噬的影响[J].中国当代医药,2013,20(7):11-13. 被引量:13