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辛伐他汀对慢性心力衰竭患者心功能的影响

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摘要 目的:观察辛伐他汀对慢性心力衰竭患者心功能和高敏C反应蛋白的影响。方法:将41例慢性心力衰竭的患者随机分为两组,对照组给予强心剂、利尿剂、受体阻滞剂、血管紧张素转换酶抑制剂等常规治疗,治疗组在上述治疗的基础上加用辛伐他汀10mg/日。观察治疗前及治疗后3个月心功能分级,测量左室射血分数(LVEF)、左室收缩末容积指数(LVESVI)及左室舒张末容积指数(LV-EDVI)。同时观察患者高敏C反应蛋白的变化。结果:治疗组在3个月后心功能、LVEF、LVEDVI、LVESVI较对照组有改善,且高敏C反应蛋白较对照组下降(P<0.05)。结论:辛伐他汀可以改善心功能,降低高敏C反应蛋白。
出处 《中国社区医师(医学专业)》 2008年第15期22-22,共1页
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