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保心丸对实验性动脉粥样硬化及高脂血症动物的药效学研究 被引量:14

Pharmacodynamic Studies on Effects of Baoxin Pill on Experimental Atherosclerosis and Hyperlipidemia in Rabbits and Rats
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摘要 采用家兔动脉粥样硬化(AS)模型和大鼠高脂血症模型,观察中药保心丸的作用。结果显示:保心丸能提高6-酮-PGF1α/TXB2比值;对照药诺衡无此作用。保心丸和诺衡对血液流变学均有明显改善作用,且诺衡作用更显著。保心丸可显著抑制血小板聚集,其作用与阿斯匹林相当。 The effects of Baoxin pill was investigated in rabbits with atherosclerosis and rats with hyperlipidemia. The results showed that the pill could regulate the ratio of 6 ketone prostaglandin F 1α /thromboxane B 2, while gemfibrozil as a reference drug had no such effect. The pill as well as gemfibrozil was observed to improve hemorheological parameters. Baoxin pill could also inhibit platelet aggregation just as aspirin did in the hyperlipidemia rats.
出处 《中国实验方剂学杂志》 CAS 1997年第5期7-9,共3页 Chinese Journal of Experimental Traditional Medical Formulae
关键词 保心丸 方剂 中药 动脉粥样硬化 高脂血症 atherosclerosis, hyperlipidemia, Baoxin pill, gemfibrozil, aspirin
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