摘要
采用ＡＰＡＡＰ法，用小鼠抗大鼠Ｔ细胞表型的单抗测定抗喘药双奇保肺冲剂（以下简称“冲剂”）对大鼠外周血中Ｔ淋巴细胞亚群ＣＤ４细胞、ＣＤ８细胞数及ＣＤ４细胞与ＣＤ８细胞数的比值的影响，并测定对其免疫器官重量的影响。环磷酰胺（ＣＹ）为药物对照组。结果显示“冲剂”可显著降低被ＣＹ增高的大鼠ＣＤ８细胞数，明显增高被ＣＹ降低的ＣＤ４细胞与ＣＤ８细胞的比值。冲剂使大鼠脾脏重量及胸腺重量增加。结果表明：“冲剂”有增强免疫功能的作用。
Effects of Shunangqi Baofei Chongji(CJ) on the CD 4 and CD 8 cells and its ratio of CD 4 and CD 8 in rat blood detected by anti rat CD 4 or CD 8 McAb using APAAP assay Cyclophosphamidum(CY) is used as a control group The results show that CJ decreases CD 8 cells increased by CY,it raises the ratio of CD 4/CD 8 reduced by CY;CJ increases weights of thymus and spleen of rats It indicates that the effects of “Chongji” antiasthma are related to their immune function
出处
《天津医科大学学报》
1997年第3期6-9,共4页
Journal of Tianjin Medical University
基金
天津卫生局科研基金
关键词
双奇保肺冲剂
中药品
T淋巴细胞亚群
药理
哮喘
Baofei Chongji
bronchial asthma
thymus and spleen indexs
CD 4 cells
CD 8 cells
