辛伐他汀与非诺贝特治疗2型糖尿病合并高血脂临床观察

Clinical observation of simvastatin and fenofibrate in the treatment of type 2 diabetes with hyperlipemia

目的:探讨辛伐他汀与非诺贝特治疗2型糖尿病合并高血脂症临床的疗效。方法:将120例2型糖尿病合并高血脂症患者随机分为3组;辛伐他汀组、非诺贝特组、辛伐他汀与非诺贝特组;分别用药观察2型糖尿病合并高血脂症的疗效。结果:各组治疗后血清TC、LDL-C、TG均比治疗前下降,HDL-C比治疗前上升。联合用药组:TC、LDL-C、TG三项水平下降的幅度及升高HDL-C的幅度均高于单独用药的两组。结论:辛伐他汀与非诺贝特治疗2型糖尿病合并高血脂症临床的疗效满意。

Objective ：To investigate the curative effect of simvastatin and fenofibrate in the treatment of type 2 diabetes with hypertipemia.Methods：120 patients with type 2 diabetes with hypertipemia were randomly divided into three groups,namcty simvastatin group,fenofibrate group and simvastatin and fenofibrate group;their results were observed respectively after treatment,the serum levels of TC,LDL-C and TG in each group all decreased,while the serum level of HDL-C increased.The ranges of decreased level of serum TC, LDL-C and TG and increased level of serum HDL-C in simvastatin and fenofibrate group were all higher compared with those in two drugs used alone.Conclusion：The curative effect of simvastatin combined with fenofibrate in type 2 diabetes with hyperlipemia is satisfactory.