精氨酸增强梗阻性黄疸细胞免疫功能及其降低感染的临床疗效观察

Observation of increasing cellular immunity and reducing infection in obstructive jaundice with arginine

研究非精氨酸（A组）37例（含14例AOSC）和精氨酸组（B组）29例（含11例AOSC）细胞免疫变化和围手术期感染性并发症。结果显示：无论手术前，还是手术后B组CD3+、CD4+显著高于A组（P＜0．01），而B组SIL－2R显著低于A组（P＜0．01）。在AOSC术后，B组体温、WBC计数明显低于A组（P＜0．01），A组术后感染性并发症非常显著高于B组（P＜0．01）。研究表明精氨酸有显著改善梗阻性黄疸围手术期细胞免疫功能作用、增强机体抗感染能力和显著降低术后感染性并发症的发生。

Changes of cellular immunity and perioperation infection complications have been studied in 37 patients(included l4 patients in AOSC) non-arginine (group A) and 29 patients (included 11 patients in AOSC) arginine (group B). The results showed that no matter what pro or post -operation,CD3+CD4+ were higher in group B than those of group A (P<0.01),but SIL- 2R of group B was lower than of group A(P<0.01). In AOSC postoperated,temperature and WBC were lower in group B than those of group A (P<0.01),infection complications of group A were very obviously higher than those of group B (P<0.01). The study indicated that arginine can improve cellular immunity and reduce post-operated infection complications.