护肝片质量标准的提高

Improve the Quality Standard for Hugan Tablets

目的:提高护肝片的质量标准。方法:采用薄层色谱法对护肝片中五味子、猪胆粉、茵陈进行鉴别;采用高效液相色谱法测定五味子乙素和绿原酸的含量。结果:薄层色谱法可检出五味子、猪胆粉、茵陈,斑点清晰,阴性对照无干扰。高效液相色谱法测定五味子乙素、绿原酸含量。平均回收率分别为99.9%,RSD为1.1%,99.7%,RSD为1.4%(n=6)。结论:方法简单,可以用于护肝片质量控制。

Objective： To improve the quality standard for Hugan tablets. Method： Fructus schisanderae Chinensis, Pulvis fellis Suis, Herba artemisiae Scopariae were identified by TLC. The contents of γ-Schinzandrin and chlorogenic acid were determined by HPLC. Result： Fructus schisanderae Chinensis, Pulvis fellis Suis, Herba artemisiae Scopariae could be identified by TLC, the spots were clear the negative control with non-interfere. The average recoveries（ n =6） of γ-Schinzandrin and chlorogenic acid were 99.9% and 99.7% with RSD 1.1% and 1.4% （ n = 6）, respectively. Conelusion： The method is simple, it can be used for the quality control of Hugan tablets.