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5-羟色胺转运体相关基因多态性与抑郁症及其药物疗效关联性研究进展(综述) 被引量:1

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摘要 5-羟色胺假说是抑郁症发病机制的一种假说,大量研究证实5-HT系统功能紊乱会导致抑郁症等神经精神疾患发病。自1996年5-羟色胺转运体连锁区域基因多态性被报道以来备受国内外学者的关注,大多数研究者认为S等位基因与抑郁症发病及疗效差相关,L等位基因与疗效佳相关,但亦有相悖结论的报道。本文仅就该方面的研究进展作一简要综述。
作者 宋亚静 张兰
出处 《中国城乡企业卫生》 2008年第4期53-54,共2页 Chinese Journal of Urban and Rural Enterprise Hygiene
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