摘要
目的：观察双黄连粉针治疗麻疹并发肺炎的疗效。方法：随机将８１例麻疹并发肺炎患儿分为治疗组４２例和对照组３９例。治疗组采用双黄连粉针６０ｍｇ·ｋｇ－１／ｄ静滴；对照组用病毒唑１０～１５ｍｇ·ｋｇ－１／ｄ静滴。均每日１次。２组其它常规治疗相同，包括应用抗生素、镇静剂、止咳平喘、强心、吸氧、营养支持及雾化吸入法等。结果：治疗组治愈３６例（８５．７％），有效５例（１１．９％），无效１例（２．４％）；对照组治愈２６例（６６．７％），有效９例（２３．１％），无效４例（１０．２％）。２组治愈率比较有显著性差异（Ｐ＜０．０５）。平均退热、止咳平喘、口罗音消失和住院时间的比较，治疗组均明显优于对照组（Ｐ均＜０．０１）。结论：双黄连粉针治疗麻疹并发肺炎具有症状改善快、肺口罗音消失快、住院时间缩短、无明显毒副作用等特点，故可作为麻疹并发肺炎的首选治疗药物。
Objective:To observe the therapeutic efficacy of “shuang huang lian” powder for injecting on treating measles complicated by pneumonia.Methods:Eightyone cases of infant pneumonia accompanied from measles were divided into treatment group ( n =42) and control group ( n =39 ) randomly.Treatment group was treated with “shuang huang lian” powder for injecting 60 mg·kg -1 /d for intravenous drip qd,while control group were treated with virazole 10￣15 mg·kg -1 /d for intravenous drip qd.In addition,there were no differences of routine therapy between 2 groups,such as antibiotic,sedative,controlling cough and breathless,cardiotonic,oxygen inhaled,nutrition support,atomization etc.Results:In treatment group,36 cases were cured (85 7%),5 cases were improved(11 9%),1 case was no changed(2 4%);in control group,26 cases were cured (66 7%),9 cases were improved(23 1%),4 cases were no changed (10 2%).There has an obvious difference of full recovery rate between 2 groups( P <0 05).On the other hand,the elimination time of certain symptoms,such as fever,cough,breathless,rale etc in treatment group was superior to control group (all P <0 01).Conclusions:There have certain characteristic of “shuang huang lian” powder for injecting on treating infant measles complicated by pneumonia,such as improving symptom and eliminating pulmonary rale rapidly,shortening the admission days and no sideeffect etc.
