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卡氏肺孢子虫感染与宿主免疫应答反应的研究进展 被引量：6

Study and advancements in infection and host immune response of pnemocystis carinii
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摘要 卡氏肺孢子虫是一种重要的机会性致病病原体,能对人体及哺乳动物的健康造成严重的危害。本文就目前国内外学者对卡氏肺孢子虫感染、宿主的免疫应答及影响因素等方面的研究做一综述。 pneumocystis carinii（PC）,a very important opportunistic pathogen,harms health of human and mammals.The infection and it＇s host immune response of PC are summarized in this review.
作者 任一鑫 郑莉莉 秦元华 崔昱
机构地区 大连医科大学寄生虫学教研室
出处 《大连医科大学学报》 CAS 2008年第4期390-393,共4页 Journal of Dalian Medical University
基金 辽宁省教育厅科学研究计划资助项目(2004D103)
关键词 卡氏肺孢子虫 PCP 宿主免疫应答 pneumocystis carinii PCP host immune response
分类号 R383 [医药卫生—医学寄生虫学] R392 [医药卫生—免疫学]
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参考文献23

  • 1Icenhour CR, Kottom TJ, Limper AH. Pneumocystis mela- nins confer enhanced organism viability[ J]. Eukaryot Cell, 2006,5(6) :916 -923.
  • 2Wright TW, Pryhuber GS, Chess PR, et al. TNF receptor signaling contributes to chemokine secretion, inflammation, and respiratory deficits during Pneumocystis pneumonia [ J ]. Immunol, 2004,172 (4) :2511 - 2521.
  • 3Beck JM,Blackmon MB,Rose CM,et al. T Cell Costimulatory Molecule Function Determines Susceptibility to Infection with Pneumocystis carinii in Mice [ J ]. Immunol, 2003, 171 (4) : 1969 - 1977.
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  • 5Baumgartner R, Durant PJ, van Gessel Y, et al. Evidence for the requirement of T cell costimulation in the pathogenesis of natural Pneumocystis carinii pulmonary infection [J]. Microb Pathog,2002, 33(5) :193 -201.
  • 6Steele C,Zheng M, Young E, et al. Increased host resistance against Pneumocystis carinii pneumonia in gammadelta T - cell - deficient mice : protective role of gamma interferon and CDS( + ) T cells[J]. Infect Immun, 2002 , 70 (9) :5208 -5215.
  • 7McAllister F,Steele C,Zheng M, et al. T cytotoxic - 1 CD8 + T cells are effector cells against pneumocystis in mice [J]. Immuoul,2004, 72(2):1132 -1138,
  • 8Lund FE,Schuer K,Hollifield M,et al. Clearance of Pneumocystis carinii in mice is dependent on B cells but not on P carinii - specific antibody [ J ]. Immuoul, 2003, 171 (3) :1423 - 1430.
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大连医科大学学报
2008年 第4期

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