Value of relative cerebral blood volume measurement using perfusion MRI in glioma management

Neurochirurgie, 2008 Jun 21.INTRODUCTION: Neoangiogenesis is a critical feature that can differentiate high- grade from low- grade glioma. Conven-tional MR imaging does not assess this histological feature accurately. The goal of this study was to evaluate the gain in rel-ative cerebral blood volume measurement using perfusion MRI in the management of cerebral gliomas. MATERIALS

INTRODUCTION： Neoangiogenesis is a critical feature that can differentiate high-grade from low-grade glioma. Conventional MR imaging does not assess this histological feature accurately. The goal of this study was to evaluate the gain in relative cerebral blood volume measurement using perfusion MRI in the management of cerebral gliomas. MATERIALS AND METHODS： Between 1998 and 2001, 32 histologically proven glial tumors were assessed by petfusion MRI using echoplanar imaging （EPI） and gradient-echo techniques. Relative cerebral blood volume （rCBV） was measured in all patients and compared to histological data.