期刊文献+

初诊2型糖尿病胰岛素治疗疗效观察

下载PDF
导出
摘要 分析短期应用胰岛素治疗的初诊T2DM36例,以同期口服药物治疗的初诊T2DM47例为对照。按初诊时空腹血糖(FBG)浓度分为A组FBG〈13.9mmol/L,B组FBG13.9-15.6mmol/L,C组FBG〉15.6mmol/L。观察2~3月后各组FBG、P2hBG、HbA1c变化情况。结果:B组和C组胰岛素明显优于对照组(P〈0.05)。结论:FBG≥13.9mmol/L有短期使用胰岛素治疗的指征。
出处 《实用糖尿病杂志》 2008年第4期22-23,共2页 Journal of Practical Diabetology
  • 相关文献

参考文献3

二级参考文献10

  • 1李光伟,宁光,周智广.2型糖尿病早期胰岛素强化治疗改善胰岛β细胞功能——是现实还是梦想?[J].中华内分泌代谢杂志,2006,22(4):309-312. 被引量:223
  • 2llkova H,Glaser B, Tunckale A, et al. Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment. Diabetes Care, 1997,20 : 1353-1356.
  • 3Floch JPL, Escuyer P, Baudin E, et al. Blood glucose area under the curve : methodological aspects. Diabetes Care, 1990,13 : 172-175.
  • 4Li Y, Xu W, Liao Z, et al. Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of β-cell function. Diabetes Care, 2004,27:2597-2602.
  • 5Park S, Choi SB. Induction of long-term normoglycemia without medication in Korean type 2 diabetes patients after continuous subcutaneous insulin infusion therapy. Diabetes Metab Res Rev, 2003, 19 : 124-130.
  • 6Kilpatrick ED, Robertson RP. Differentiation between glucose-induced desensitization of insulin secretion and beta-cell exhaustion in the HITT15 cell line. Diabetes, 1998, 47: 606-611.
  • 7Brownlee M. A radical explanation for glucose-induced beta cell dysfunction. J Clin Invest, 2003,112:1788-1790.
  • 8Rustenbeck I, Wienbergen A, Bleck C. Desensitization of insulin secretion by depolarizing insulin secretagogues. Diabetes, 2004,53 : S140-S150.
  • 9Fasshauer M, Paschke R. Regulation of adipocytokines and insulin resistance. Diabetologia, 2003,46 : 1594-1603.
  • 10Zhao YF, Feng DD, Cben C. Contribution of adipocyte-derived factors to beta-cell dysfunction in diabetes. Int J Biocbem Cell Biol, 2006,38 : 804-819.

共引文献103

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部