两种不同雾化吸入糖皮质激素法对支气管哮喘患者治疗效果的观察

目的观察两种不同糖皮质激素吸入法对支气管哮喘患者治疗的效果。方法2007年1—12月对41例患者交替接受两种雾化吸入法治疗，即单日治疗经口吸入，双日治疗经面罩吸入，分别进行41次，共82次吸入治疗。评价两种方法治疗前后患者血氧饱和度（sa02）及血氧饱和度差值（△SaO2）情况，患者气促缓解程度及耐受情况。结果治疗前两种雾法吸入法患者SaO2比较，差异无统计学意义（P〉0．05）；治疗后雾化面罩吸入法患者SaO2、△SaO2明显改善，两种方法比较，均P〈0．01，差异有统计学意义；雾化面罩吸入法较经口吸入法更加有效地缓解患者呼吸困难症状，两组比较，P〈0．01，差异有统计学意义；两组耐受率比较，P〉0．05，差异无统计学意义。结论雾化面罩吸入糖皮质激素法较经口吸入法对控制支气管哮喘患者急性发作效果更好，而且患者耐受性好，提高了患者舒适度，值得临床推广应用。

Objective To compared the effects and tolerance of ventolinum atomizing inhalation via oral or via atomizing veil in treating patients with bronchial asthma. Methods 41 Patients with bronchial asthma in acute episode stage were received ventolinum atomizing inhalation via oral or via atomizing veil in different time respectively. SaO2 as well as △SaO2 were measured. Breathlessness relief was evaluated. The cases that could not tolerance the treatment were also recorded, Results Levels of SaO2 in two groups were not significartly different hot＇ore treatment （ P 〉 0. 05 ）. Both A Sa02 and breathlessness were improved after two atomizing inhalation treatments, but the ASa02 was increaesd more significant in atomizing inhalation vial atomizing veil group than in via oral greup（P 〈0.01）. Furthermore, atomizing inhalation vial atomizing veil was more easy tolerance, but not reach statistic significant （P 〉 0.05）. Conclusion Vcntolinum atomizing inhalation via atomizing veil is better effect and tolerance in treating patients with bronchial asthma.