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ABCC4基因与妊娠肝内胆汁淤积症相关性研究进展

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摘要 妊娠期肝内胆汁淤积症fintrahepatic cholestasis of pregnancy，ICP）病因复杂，目前研究认为遗传因素在其发病机制中起着相当关键的作用。其中ABCC4基因与ICP的发病尤为密切。肝细胞以胆固醇为原料合成初级胆汁酸．7α-羟化酶催化这一反应的限速酶．合成的胆汁酸通过毛细胆管膜分泌入胆管系统进入十二指肠。
作者 卢斌 刘淮
机构地区 南昌大学医学院 江西省妇幼保健院
出处 《江西医药》 CAS 2008年第7期740-742,共3页 Jiangxi Medical Journal
关键词 ABCC4基因 妊娠肝内胆汁淤积症
分类号 R714.255 [医药卫生—妇产科学]
  • 相关文献

参考文献15

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二级参考文献21

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共引文献17

江西医药
2008年 第7期

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