经腹部超声引导注射无水乙醇配合药物治疗卵巢囊肿临床研究

Clinical Research of Abdominal Ultrasound-guided Injection of Ethanol and Matching Drug in Treatment of Ovarian Cyst

目的评价经腹超声引导下穿刺卵巢囊肿,抽吸囊液,注入无水乙醇,并配合促性腺激素释放激素激动剂治疗卵巢囊肿的疗效。方法将126例卵巢囊肿患者随机分为治疗组(65例)和对照组(61例)。治疗组在超声介入下经腹穿刺抽吸囊液,注入无水乙醇后,另给予曲普瑞林3.75mg/次,肌注,每月一次,连用3个月;对照组经穿刺治疗后未予药物治疗。对两组的总有效率和复发率进行比较。结果经治疗后,治疗组总有效率为96.9%,明显高于对照组的80.3%;治疗组复发率为6.4%,明显低于对照组的18.4%,差异均有统计学意义(P<0.05)。结论经腹超声介入穿刺配合药物治疗卵巢囊肿是一种安全、有效、经济简便的方法,值得临床推广应用。

Objective To evaluate the effect of treatment by transabdominal ultrasound in pricking ovarian cyst, sucking hydrated fluid, influxing dehydrated alcohol and matching GnRHa to cure ovarian cyst. Methods Totally 126 cases of ovarian cyst were randomly divided into treatment group （n = 6.5） and the control group （n = 61）. Ultrasound intervention in the treatment group was performed under the abdominal puncture sucking hydrated fluid, influxing dehydrated alcohol, intramuscular injection of PuRuilin （3. ？.5 mg/times） once a month on 3 successive months. None of the patients in the control group received any drug treatment after the puncture. The total efficiency rate and the recurrence rate in the two groups were compared. Results After the treatment, the cure rate of therapy group was 96.9 % ,which was significantly higher than that of the control group （80.3 % ） （P 〈 0.0.5）. The recurrence rate of therapy group was 6.4 %, which was significantly lower than that of the control group （18.4 % ） （P 〈 0.0.5）. Conclusions Pricking ovarian cyst of ovary and matching drug treatment guided by transabdominal ultrasoud is a secure and effective method, without influencing ovarian function.