原发性胃恶性淋巴瘤32例诊治体会

Primary gastric malignant lymphoma:Clinical experience of 32 cases

目的:探讨原发性胃恶性淋巴瘤的临床特点,以提高该病的诊治水平。方法:对经病理确诊的32例原发性胃恶性淋巴瘤临床资料进行总结、分析。结果:CT检查对胃恶性淋巴瘤的术前诊断率55.6%,胃肠钡餐对胃恶性淋巴瘤的术前诊断率为47.6%,胃镜对胃恶性淋巴瘤的诊断率仅有34.7%,而术前胃镜和胃肠钡餐联合应用可使胃淋巴瘤的诊断率提高到69.3%。病理类型均为非何杰金氏淋巴瘤,其中B淋巴细胞性18例,T淋巴胞性3例,浆样细胞型1例,T、B双淋巴细胞性1例,5年生存率65.6%。结论:胃恶性淋巴瘤的术前诊断率低,联合应用多种诊断方法将有助于提高胃恶性淋巴瘤的术前诊断率;手术是治疗的主要手段。

Objective ： To investigate the clinical features of primary gas- tric malignant lymphoma（PGML） for improving diagnosis and treatment of this disease. Methods ： Clinical data of 32 patients with PGML confirmed pathologically were reviewed and analyzed. Results： Pre-operation diagnosis showed that 55.6% could be confirmed by CT scan, 47.6% by intestinal barium examination, 34.7% by the gastroscopy - but up to 69.3% by combination of the gastroscopy and intestinal barium examination. All cases belonged to non-Hodgkin＇s lymphoma in terms of pathological types, among which 18 cases were B-lymphocyte type; 1, T-lymphocyte; 1, plasnacttuiubd lymphocyte and another 1, combined with T-and B-lymphocyte. 5-year survival rate was 65.6%. Conclusion ： Pre-operation diagnosis rate is low, but combined examination can improve the diagnosis and the treatment still rely on surgical procedure.