糖尿病对冠脉支架术后近期随访结果的影响

Impact of the diabetes mellitus on recent clinical events after coronary intervention

目的对冠脉支架术后,糖尿病对近期临床不良事件(MACE)的发生率是否有影响进行研究。方法2000-2006年我院115例冠脉支架术后的患者,50例置入金属裸支架(BMS),65例置入药物涂层支架(SES)。分组:①无糖尿病对照组;②糖尿病组。比较MACE的发生率。结果两组临床资料差异无统计学意义,冠脉病变和术中支架放置差异无统计学意义,置入BMS组,糖尿病与对照组MACE发生率分别为(34.4%和20.0%,P<0.05),差异有统计学意义;置入SES组,MS与对照组MACE发生率分别为(16.0%和9.5%,P<0.05),差异有统计学意义。结论糖尿病是冠心病的独立危险因素,且合并糖尿病的冠心病冠脉血管病变较严重,糖尿病对于冠脉支架术后近期MACE发生率有显著影响。

Objective To compare the impact of diabetes mellitus on recent clinical events after coronary intervention. Methods From 2000 to 2006,a total 115 patients,50 with BMS,65 with SES. Group： （1）DM DCM group; （2）NO DM control group To compare the incidence of MACE. Results There is not difference in clinical date and lesion of coronary artery and stents implantation between two groups. In BMS implanted group：the incidence of MACE is signifficant difference between DM group and NO DM control group（34.4% vs 20.0%,P〈0.05）. In SES implanted group：the incidence of MACE is also difference between DM group and NO DM control group （16.0% vs 9.5%,P〈0.05）. Conclusion DM is independent risk factor artery.But patients with DM have an increased risk for target lesion revascularization or a greater MACE rate compared with control patients during a 12 monthfollow-up period after bare-metal or drug-eluting stent placement.