西普妙治疗抑郁症的临床疗效观察

Clinical curative effect of Citalopram on patients with depression

目的评价西普妙治疗抑郁症的临床疗效。方法入选96例病人,随机分为治疗组54和对照组42例,2组病人的一般情况及病情程度等具有可比性。对照组给予多虑平片50mg,3次/d;治疗组给予西普妙片20mg,1次/d。疗程均为8周,8周后观察临床疗效。结果治疗组疗效明显优于对照组。不良反应发生率低。结论西普妙具有较好的抗抑郁作用,且不良反应少。

Objective To observe the clinical effect of Citalopram on patients with depression. Methods In randomized trial, 54 patients with depression were taken as treatment group, 42 patients in control group. There were no statistical differences between the two groups in state of disease, general condition etc. In control group, Doxepin was given（oral dosage, 25mg, thrice a day）. Citalopram was given（20mg, daily ）for treatment group. Observation was on the clinical effect after 8 weeks. Results Treatment group had better clinical effect than control group with low side effect incidence. Conclusion Citalopram has low side effect incidence and perfect security , and has better clinical effect on patients with depression.