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脑脊液细胞学检查对新型隐球菌脑膜炎的诊断价值 被引量:6

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摘要 目的了解脑脊液细胞学检查对新型隐球菌的检出率。方法脑脊液标本用离心沉淀法收集,HE染色后镜检观察菌体形态特征,对可疑隐球菌者行PAS染色以证实。结果新型隐球菌在HE染色下有其独特的形态学特征,根据其特征可做出初步诊断,再结合PAS染色,可大大提高检出率。结论脑脊液细胞学检查对新型隐球菌的检查有一定的诊断价值,能弥补单一墨汁染色极易漏诊的缺陷,对新型隐球菌脑膜炎快速作出敏感性和特异性较高的诊断。
作者 梁委军
出处 《中国实用神经疾病杂志》 2008年第8期103-104,共2页 Chinese Journal of Practical Nervous Diseases
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  • 1谭爱莲,欧阳珊.中枢神经系统新型隐球菌病[J].中华神经精神科杂志,1993,26(4):241-243. 被引量:64
  • 2卢洪洲,曹天高,周颖杰,尹有宽,潘孝彰,翁心华.乳胶凝集试验对新型隐球菌性脑膜炎诊断及治疗的意义[J].中华传染病杂志,2005,23(3):209-211. 被引量:45
  • 3Netea MG, Brouwer AE, Hoogendoorn EH, Two patients with cryptococcal meningitis and idiopathic CD4 lymphopenia: defective cytokine production and reversal by recombinant interferon- gamma therapy. Clin Infect Dis. 2004, 39(9);e83-7
  • 4Panepinto J, Liu L, Ramos J,et al. The DEAD-box RNA helicase Vadl regulates multiple virulence-associated genes in Cryptococcus neoformans. J Clin Invest. 2005 Mar 1: 115(3): 632-641
  • 5Okabayashi K, Kano R, Watanabe S,et ah Expression of capsule-associated genes of Cryptococcus neoformans. Mycopathologia.2005 Aug, 160(1):1-7
  • 6Fabricc Chretien, Olivier Lortholary, et al. Pathogenesis of cerebral cryptoeoccus neoformanns infection after Fungemia. J Infect. Dis.2002,AuglS:186 (4) :522-30
  • 7Yun C. Chang,H- Monique F. Stins,2+ Michael J. McCaffery,et al. Cryptocoecal Yeast Cells Invade the Central Nervous System via Transcellular Penetration of the Blood-Brain Barrier. INFECTION AND IMMUNITY, Sept. 2004. p. 4985-4995
  • 8Malessa R, Krams M, Hengge U, et al. Elevation of intracranial pressure in acute AIDS related cryptococcal meningitis. Clin Investig 1994:72:1020-6
  • 9T. G.. M. Bauters,D. Swinne,V. Stove.et ahDetection of Single Ceils of Cryptococcus neoformans in Clinical Samples by Solid-Phase Cytometry. Journal of clinical microbiology,Apr. 2003,41(4): 1736-1737
  • 10Sugiura Y, Homing M. Yamamoto T. Difficulty in diagnosing chronic meningitis caused by capsule-deficient Cryptococcus neoformans.J Neurol Neurosurg Psychiatry. 2005 Oct;76(10): 1460-1

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