N-氯代邻苯二甲酰亚胺的合成研究

Study on synthesis of N-chlorophthalimide

以苯酐为原料,与尿素反应制得邻苯二甲酰亚胺后,采用在醋酸水溶液中滴加次氯酸钠的方法制备N-氯代邻苯二甲酰亚胺,优化了反应的各种条件,使产品收率达94%以上。

Phthalimide was synthesized by the reaction between phthalicanhydride and urea. Then N - chlorophthalim- ide was prepared by droping hypochlorite into the solution of acetic acid,water and phthalimide. The reaction condition was optimized, and the product yield reached to over 94%.