珠海及周边地区哮喘患儿过敏原状况及粉尘螨滴剂舌下含服疗效研究

Study on the condition of allergens in children with asthma in and around Zhuhai district and clinical efficacy of sublingual immunotherapy with dermatophagoides farinae driops in asthma

【目的】探讨珠海及周边地区哮喘患儿过敏原状况以及粉尘螨滴剂舌下含服在哮喘治疗中的意义。【方法】应用屋尘螨、粉尘螨等25种常见过敏原对367例哮喘的患儿进行皮肤点刺过敏原检测。检测血清IgE,同时对粉尘螨阳性的哮喘患儿采用粉尘螨滴剂舌下含服治疗。【结果】过敏原检测阳性率为71.3%。阳性率最高依次为屋尘螨、粉尘螨和海产品类。粉尘螨脱敏治疗有效率为86.53%。【结论】珠海及周边地区哮喘患儿的过敏原最常见为屋尘螨,粉尘螨及海产品;粉尘螨滴剂舌下含服是治疗哮喘的重要措施之一。

[Objective] To investigate the type and the positive rates of allergens in children with asthma in and around Zhuhai district and explore the meanings of sublingual immunotherapy with dermatophagoides farinae driops（DFD） in asthma. [Methods] Twenty-five common allergens such as house dust and dermatophagoides and serum total IgE were detected in 367 children with asthma. And giving sublingual immunotherapy with DFD to the children with the positive of dermatophagoides. [Results] The total positive rates of allergens was 71.3%,the positive rates of dermatophagoides, house dust and product in the sea were the three highest ones. The effective rate of desensitization with DFD was 86.53%. [Conclusions] The most eommon allergens in ehildren with asthma in and around Zhuhai distriet are dermatophagoides and house dust and product in the sea;It is may be one of the most important means of sublingual immunotherapy with DFD to treat children＇s asthma.