原发性遗尿症的112例临床研究

Clinical study of primary nocturnal enuresis in 112 children

【目的】通过单纯弥凝、单纯干床训练和两者合并治疗原发性夜间遗尿症(primary nocturnal enuresis,PNE)的研究,探讨儿童PNE的较佳治疗方法。【方法】对112例PNE患儿进行问卷调查,并予以弥凝、干床训练和两者合并3种方案治疗PNE3个月,治疗结束时和结束后追踪3月观察其疗效和复发率。【结果】疗程结束时和追踪观察3月两者合并治疗有效率、治愈率高于单一治疗组,差异有显著性(P<0.05)。疗程结束后追踪3月单纯弥凝组复发率高于单纯干床训练组和两者合并治疗组,差异有显著性(P<0.05)。【结论】两者合并治疗PNE降低了单一弥凝治疗的复发率,提高了单一治疗的疗效,但远期疗效需进一步追踪观察。

[Objective] To investigate the better treatment on children with primary nocturnal enuresis（PNE） by different treatments including oral DDAVP, dry bed training,and combined treatment on PNE. [Methods] 112 children with PNE were investigated by means of questionnaires. Therapeutic effect were studied by that 112 children were treated with oral DDAVP, dry bed training and combined treatment for 3 months. Relapse rate of different treatments were studied for 3 months after stopping treatment. [Results] Effective power of treatment of combined treatment were significantly higher than that of dry bed training or DDAVP. Relapse rate of oral DDAVP was higher than that of dry bed training and combined treatment. [Conclusion] Combined treatment have relatively low relapse rate and relatively high efficacy, but its prostecdtive efficacy on PNE needs further study.