CBCL用于重型地中海贫血患儿的初步调查研究

Primary study on psychic behavior in children with thalassemia major by Child Behavior Check-List

【目的】探讨重型地中海贫血（简称地贫）患儿的心理行为有无异常。【方法】采用Achenbach儿童行为量表（Child Behavior Check—List，CBCL）对学龄期和青少年期重型地中海贫血患儿65例及81例正常儿童进行测试。【结果】重型地中海贫血患儿组活动能力、社交情况和学校情况均明显低于对照组（P〈0．01）。行为问题中，在6～11岁男童中，地贫组患儿在分裂样、抑郁、交往不良、多动、攻击性等因子上得分显著高于正常对照组（P〈0．05）。在6～11岁女童中，地贫组患儿在抑郁、社交退缩、多动和攻击性等因子上得分显著高于正常对照组（P〈0．05）。在12～16岁男童中，地贫组患儿在体诉、分裂样、交往不良、不成熟、敌意和攻击性等因子上得分显著高于正常对照组（P〈0．05）。在12～16岁女童中，地贫患儿在焦虑强迫、体诉、分裂样、抑郁退缩、不成熟和攻击性等因子得分显著高于正常对照组（P〈0．05）。【结论】重型地中海贫血患儿存在社会能力差和焦虑、抑郁、社交退缩、和多动等行为问题，有必要在治疗躯体同时对患儿和患儿家庭给予精神支持和社会心理干预。

[Objective] To research the behavior of children with thalassemia major（TM） and determine the effects of the disease on behavior. [Method] 65 children with TM and 81 case of age-matched normal children were investigated for behavior problems by using Child Behavior Check-list （CBCL）. [Results] As determined by CBCL,children with TM had lower activities,social competence and school aspect than those in control group （P〈0.01）. Compared with control group,TM group were significantly higher in total behavior problems raw scores, the male group in 6 to 11 years old had the higher levers in schizoid, depression, social problem, hyperactivity and aggression than those of control group; the female group in 6 to 11 years old had the higher levers in depression, withdraw, hyperactivity and aggression; the male group in 12 to 16 years old had the higher levers in somatic complain, schizoid, social problem, immaturity, hostility and aggression; the female group in 12 to 16 years old had the higher levers in anxiety/obsession, somatic complain, schizoid, depressed/withdraw, immaturity and aggression. [Conclusions] Children with TM have lower activities, social competence and school aspects and behavior problems in depression, anxiety, withdraw, social problem, aggression, hyperactivity and so on.