低分子肝素钙伍用脉络宁注射液联合治疗急性脑梗死的疗效观察

The Clinical Observation of Acute Cerebral Infarction Therapy with Low Molecular Weight Heparin Calcium and Mailuoning Injection

目的:观察低分子肝素钙、脉络宁注射液联合应用对急性脑梗死的疗效。方法:83例急性脑梗死患者随机分成2组,治疗组用低分子肝素钙0.4ml,每12小时腹部脐周交替注射1次,共用7天;脉络宁注射液20ml加入250ml0.9%盐水或5%葡萄糖注射液静滴,1次/天,共用15天。对照组应用腹蛇抗栓酶0.75U加入250ml0.9%盐水静滴,1次/天,共用15天。分别观察2组治疗前后血液学改变及临床疗效。结果:显效率,治疗组71.4%,对照组50.05%;总有效率,治疗组93.9%,对照组85.3%,2组间差异显著。结论:低分子肝素钙,脉络宁注射液联合应用治疗急性脑梗死,其改善血液学及临床疗效方面明显优于蝮蛇抗栓酶。且安全有效。

Objective：To observe the effect of acute cerebral infarction therapy with low - molecular -weight heparin calcium and Mailuoning injection. Methods： To divide randomly 83 cases of acute cerebral infarction patients into two groups, to apply low - molecular- weight heparin calcium 0. 4 ml for Treatment Group, an alternate injection once every12 hours at abdoman perlumbilicus continuously for seven days; 20 ml of Mailuoning in 250 ml of 0. 9% brine or 5% glucose intravenous injection, once a day continuously for 15 days. To apply 0. 75 U of abdominal snake antithrombotic with 250 ml of 0.9% saline infusion for Control Group once a day continuously for 15 days. To observe separately the two groups by changes before and after in hematology and their clinical treatment effect. Results： Treatment Group has 71.4 percent of significant efficiency. Control Group has 50. 05 percent The total efficiency of Treatment Group is 93.9% , Control Group 85.3%. The difference between the two groups is significant. Conclusion： Combined treatment of low-molecular-weight heparin calcium and Mailuoning injection for acute cerebral infarction can improve in hematology and its clinical efficacy is superior to Ahylysantinfarctase. And it is safe and effective.