依达拉奉对急性脑梗死患者血清丙二醛表达的影响

Effect of Edaravone on the Expression of Serum Malondialdehyde(MDA) of Patients with Acute Cerebral Infarction

目的:探讨依达拉奉在急性脑梗死时的神经保护作用。方法:120例急性脑梗死患者随机分为对照组和依达拉奉组,检测治疗前和治疗后7d、14d患者血清丙二醛的含量及两组的疗效。结果:依达拉奉组疗效显著优于对照组(P<0.05),且治疗后患者血清丙二醛减少,与对照组比较有显著性差异(P<0.05)。结论:早期急性脑梗死患者给予依达拉奉治疗可以降低脑细胞的损害,有利于病情的恢复。

Objective：To explore the neuroprotective effect of edaravone on acute cerebral infarction. Methods： 120 cases of acute cerebral infarction patients were randomly divided into two groups and edaravone group, detection and treatment before and after 7 d, 14d in patients with MDA content and the effect of the two groups. Results： Edaravone group effect was significantly superior to the control group （ P 〈 0. 05 ）, and after treatment in patients with MDA reduced, compared with the control group there were significant differences （ P 〈 0.05 ）. Conclusion： Early acute infarction patients treatment given to edaravone can reduce brain cell damage and is conducive to the resumption of illness.