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病态巨核细胞在骨髓增生异常综合症(MDS)分期中分布规律的探讨 被引量:3

Discussion on Distribution Law of Sick Megakaryocyte in MDS during Various Stages
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摘要 目的:通过对30例MDS患者骨髓片中5种病态巨核细胞分布规律的观察,探讨其分布规律与疾病预后的关系。方法:采用单抗CD41免疫酶标染色对30例已确诊MDS的骨髓片染色,于光学显微镜下,仔细观察染色后病态巨核细胞的数量、形态和种类。结果:病态巨核细胞特别是淋巴样小巨核细胞数量的多少在MDS这类疾病的不同时期分布有一定差异。结论:病态巨校细胞种类和数量与MDS的转归和预后存在一定的相关关系。 Objective:To observe distribution law of 5 sick megakaryoeytes through 30 MDS cases of bone marrow smears and to discuss the correlation between the distribution law and prognosis of disease. Methods: To observe closely the bone marrow smears of the 30 cases of confirmed MDS by monoclonal antibody CD41 immuno - enzyme - labelling staining with optical microscope. To observe carefully the number, number, morphology and species of sick megakaryocyte after staining. Results: Sick megakaryocyte, especially the number of megakaryocyte and its distribution of MDS during various stages are different. Conclusion: There is some correlation between species and number of sick megakaryocytes and the outcome and prognosis of MDS.
出处 《中国医药导刊》 2008年第4期604-604,606,共2页 Chinese Journal of Medicinal Guide
关键词 病态巨核细胞 分布规律 骨髓增生异常综合症 Sick megakaryocyte Distribution law Myelodysplastic syndrome
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