167例老年糖尿病患者医院真菌感染临床分析

Analysis of Nosocomial Fungal Infection in 167 Old Patients with Diabetes

【目的】探讨老年糖尿病患者并发医院真菌感染的危险因素、临床特点和防治对策。【方法】回顾性调查分析167例老年糖尿病患者并发真菌感染的临床特点。【结果】感染部位以下呼吸道为主(41.4%),泌尿道次之(23.7%);167例患者共培养出真菌198株,白色假丝酵母菌占第1位(54.0%),热带假丝酵母菌占第2位(21.2%)。【结论】老年糖尿病患者发生医院真菌感染与血糖浓度、糖尿病并发症及抗菌药物长期应用和侵入操作等危险因素密切相关。

[Objective] To investigate and analyze the risk factors, clinical characteristics and prevention countermeasures of nosocomial fungal infection in old patients with diabetes. [Methods]The clinical data of nosocomial fungal infection in 167 cases from the old patients with diabetes were reviewed and analyzed retrospectively. [Results] Among 167 cases the infection occurred predominantly in lower respiratory tract （41. 4%） and the second in urological tract （23.7%）. Of 198 strains of fungi from 167 patients, the first was Candida albicans（54.0 % ）, and the second was C. tropicalis（21.2 % ）. [Conclusion] The causes of nosocomial fungal infection in old patients with diabetes are highly associated with the risk factors such as blood glucose concentration, complications of diabetes,antibiotics, invasive operation, etc.