糖化血红蛋白测定与脑梗死患者血糖升高相关性探讨

Discussion on Relativity of Glycosylated Hemoglobin Detection and Increasing Blood Sugar of Cerebral Infarction Patient

目的探讨糖化血红蛋白测定与脑梗死患者血糖升高的相关性。方法选择符合脑梗死诊断标准患者89例,分为既往有糖尿病组和无糖尿病组。另选100例无糖尿病及其它主要器官病变者为正常对照组。采空腹静脉血测定糖化血红蛋白。结果糖尿病组和无糖尿病组血糖水平明显高于正常对照组(P<0.01),但糖尿病组与无糖尿病组之间血糖水平差异无显著性(P>0.05)。糖尿病组空腹血糖水平与糖化血红蛋白水平呈显著正相关(P<0.01);与正常对照组糖化血红蛋白比较有显著性差异(P<0.01);与无糖尿病组糖化血红蛋白比较亦有显著性差异(P<0.01);无糖尿病组糖化血红蛋白与正常对照比较无显著性差异(P>0.05)。结论糖化血红蛋白测定,是早期鉴别脑梗死应激性高血糖和糖尿病的可靠方法,可以对脑梗死合并糖尿病进行早期干预,对选择治疗方案、判断预后等均有较大临床意义。

Objective To discuss the relationship between glycosylated hemoglobin detection and increasing blood sugar of cerebral infarction. Methods 89 caese of such patient divided into diabetic history group and non history diabet gourp. 100 cases of healthy adult were as control group. Glycosylated hemoglobin was detected in empty stomach. Resuits The blood glucose levels in diabetic history group and non diabetic history group were higher than that in control group. The blood glucose levels in diabetic group in empty stomach was higher than that the level of glycosylated blood glucose with positive relationship P 〈 0.01. The level of glycosylated blood glucose was similar with control group. Conclusion The detection of glycosylated hemoglobin might be reliable in early stage of cerebral infarction and diabetes that could supply the early intervemion and treatment methods selection and to assess the prognosis with clinical significance.