摘要
目前国内临床治疗的胃癌患者大部分属于进展期,早期胃癌患者较少。进展期胃癌手术切除率低,预后差。进展期胃癌行新辅助化疗能使原发肿瘤降期,能提高根治性手术切除率,有改善患者生存率的可能。本文从进展期胃癌新辅助化疗的理论基础、研究现状与进展、效果评估、化疗用药等几个方面对进展期胃癌新辅助化疗进行综述,来说明术前新辅助化疗是进展期胃癌一种有效的治疗手段。
At present, most of patients diagnosed as gastric cancer with clinical therapy belong to advanced stage in China; The patients in early stage are relatively few. While patients in advanced stage have poor prognosis in general and low rate of curative resection. Neoadjuvant chemotherapy for advanced gastric cancer can obtain downstaging, increase rate of curative resections, and has the possibility of improving survival. Neoadjuvant chemotherapy might be an effective and feasible therapeutic method for advanced gastric cancer.
出处
《国际外科学杂志》
2008年第8期540-543,共4页
International Journal of Surgery