微钙化在乳腺疾病超声诊断中的价值

Micro-calcification in ultrasound diagnosis of breast diseases

目的评价微钙化在超声诊断乳腺疾病的价值。方法收集乳腺微钙化(经钼靶摄影证实)病变患者68例,根据微钙化的钼靶摄影表现将其分为≥10 mm和<10 mm 2组;簇状分布、沿导管分布和散在分布3组。分析不同组别微钙化的超声检出率及超声对乳腺病变诊断的敏感性和特异性。结果微钙化的超声检出率为61.7%,其中恶性病变的微钙化超声检出率为84.2%,良性病变的超声检出率为33.3%。微钙化簇≥10 mm组的超声检出率为84.8%,<10 mm组检出率为40.0%;呈簇状和沿导管分布的微钙化超声检出率为72.5%,散在分布的检出率为29.4%;乳腺恶性病变超声诊断的敏感性和特异性分别为92.1%、76.7%。结论超声检查可有效识别乳腺病变内的微钙化,特别是恶性病变,其对乳腺病变的诊断与鉴别诊断具有重要临床应用价值。

Objective To evaluate the value of high-frequency ultra-sonogi＇aphy（US） in the diagnosis of breast diseases with micro-calcification. Methods Sixty-eight patients with breast micro-calcification received mammography and high-frequency US. Basced on size, micro-calcifications were divided into two groups： the ≥10 mm group and the 〈 10 mm group, also based on distribution, they were divided into the cluster, linear and scattered distribution groups. Sensitivity and specificity of US in the diagnosis of breast diseases were analyzed. Results Sensitivity aud specificity of US in breast malignant diseases with micro-calcification was 92.1% and 76.7%. 61.7% of the breast micro-calcifications were found by US, and 84.2% of them were malignant and 33.3 ok were benign （P 〈 0.05）. The detection rate of a micro-calcification cluster larger than 10mm was 84.8% and of that smaller than 10mm was 40.0% ; and the detection rate of the micro-calcification of linear distribution and cluster distribution was 72.5 % and of that scattering distribution was 29.4 %. Conclusion US can depict breast micro-calcifications, especially malignant lesions, and micro-calcification has a great value for the diagnosis of breast diseases.