莪术油中莪术二酮的分离和鉴定

Isolation and identification of curdione in zedoary oil

目的:分离鉴定莪术油中莪术二酮成分。方法:采用硅胶柱色谱的方法对莪术油的化学成分进行分离;并采用红外、气相色谱/质谱和核磁共振波谱法进行结构鉴定。结果:从莪术油中分离得到3个化合物C1,C2和C3,其中C1为莪术二酮,其在莪术油中的相对含量为11.31%。结论:该分离方法简单易行,为大量分离莪术二酮进行药理学研究提供了依据。

AIM： To study the isolation and identification of curdione from Zedoary oil. METHODS： Silica column was adopted to isolate constituents from Zedoary oil; IR, GC/MS and NMR methods were used to identify its structure. RESULTS： Three constituents were isolated from Zedoary oil, including crystal C1, C2 and C3. Crystal C1 was identified to be curdione and curdione content in Zedoary oil was 11.31%. CONCLUSION： This method is simple and convenient and it can be used to isolate more quantity of curdione for further pharmaceutical study.