纠正阴道微生态失衡对妊娠期阴道炎的治疗价值

The importance to rectify the microecological disturbance of vaginain gestational period in treating colpitis

目的通过对妊娠期阴道微生态的检测，探讨纠正阴道微生态失衡对妊娠期阴道炎的治疗价值。方法随机选取产前检查患者250例，不论有无阴道炎症状均采集阴道分泌物，行革兰染色涂片，同时查白细胞酯酶、唾液酸苷酶、过氧化氢浓度，观察阴道微生态状态，对阴道微生态失衡的患者随机采用不同的治疗方法，观察妊娠期阴道微生态失衡和阴道炎的治愈率及阴道炎的复发率。结果250例孕妇中有166例符合阴道微生态失衡的诊断，其中单纯微生态失衡者110例，占44％；阴道炎患者56例，占22．4％。在阴道微生态失衡组，经阴道微生态平衡治疗的孕妇阴道微生态正常率明显升高，阴道炎的发生率低，差异有统计学意义。在阴道炎组，经阴道微生态平衡治疗的孕妇，阴道炎的5d治愈率明显高于对照组，但10d治愈率两组比较差异无统计学意义。阴道炎的复发率治疗组明显低于对照组。结论恢复阴道微生态的平衡可缩短阴道炎治疗时间，并降低阴道炎的复发率。

Objective To detect vaginal microecosystem and discuss the importance to rectify the microecological disturbance of vagina in gestational period in treating colpitis. Methods 250 prenatal care women in our hospital were selected as samples. We collected vaginal secretion, made microecological evaluation based on Gram stained smear., and detected leukocyte esterase, concentration of hydrogen dioxide and sialic acid-anhydride esterase. Different treatrhents were used randomly to these with vaginal ecological disturbance to investigate the cure rate of microecological disturbance of vagina and colpitis,and the recrudescence rate of colpitis. Results 166 of the 250 women had microecologlcal disturbance of vagina,in the 166 women, 110 had semplice microecological disturbance of vagina and 56 had colpitis. In the group with vaginal ecological disturbance, the rate of well-balanced vaginal ecology was increased obviously and the rate of colpltis was low. The difference was of statistical significance. In the group with colpitis, after equilibrium treatment, the cure rate of colpitis in the study group was much higer than the control group after five-days＇ treatment,but no significant difference after ten-days＇ treatment. The recrudescence rate of colpitis was much lower in the study group than that in the control group. Conclusion Rectify the microecological disturbance of vagina will shorten the period of treatment and reduce the recrudescence rate of colpitis.