摘要
目的;分析肾综合症出血热(HFRS)并发肝损害的发生率、严重程度及其与HFRS病情的关系。方法:收集我院2000年1月至2007年12月收治的226例HFRS患者的临床资料,对并发肝损害的160例患者进行回顾性分析。结果:160例HFRS合并肝损害患者占HFRS患者的70.8‰,均有不同程度的食欲减退,恶心呕吐等消化道症状,肝区叩击痛41倒;肝肿大40例,重度黄疸2例。160例ALT均有不同程度升高.伴有血清TBn升高46倒,伴有血清A1b降低97例,51.2%的患者肝损害发生于少尿期,8.7%发生于发热期.重度肝损害多发生于重型、危重型。肝损害7天内恢复者72例,8~14天恢复者44例,15~21天恢复者38例,22~28天恢复者4例。160例有肝损害的患者中,2例因重度肝损害死亡。其余患者肝损害均随原发病的好转而恢复正常,无慢性化倾向。结论:肝损害程度与HFRS临床分型呈正相关,HFRS引起的肝损害是可逆的,随着原发病的好转而恢复,无慢性化倾向,其恢复时间取决于临床分型和肝损害程度。
Objective:To investigate the clinical characteristics of hemorrhagic fever with renal syndrome (HFRS) and liver damage complication, the extent of liver damage and its relationship with HFRS. Methods:Collecting clinical data of treated 226 HFRS cases from January 2000 to December 2007. Analyzing 160 cases with liver damage complication. Results: 160 patients with liver damage were 70.8% in 226 HFRS cases, they had varying gastrointestinal symptoms and signs. Two patients died in 160 cases. The remaining patients improved and with non--chronic tendency. Conclusion:The liver damage of HFRS is positive correlation with its clinical classification. HFRS caused liver damage is reversible with the improvement of primary disease and non--chronic tendency. The recovery time depends on the clinical classification and extent of liver damage.
出处
《内蒙古中医药》
2008年第7期15-17,共3页
Inner Mongolia Journal of Traditional Chinese Medicine
关键词
肾综合瘟出血热
肝损害
预后
临床分型
Hemorrhagic fever with renal syndrome
Liver damage
Prognosis
Clinical classification